Articles

Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer

Sida Huang, Sarah J Westvold, Pamela R Soulos, et al. JAMA Netw Open. 2025 Apr 1;8(4):e255322

Screening mammography promotes early detection of breast cancer and is associated with reduced breast cancer mortality. Screening history prior to diagnosis may impact stage at diagnosis and breast cancer mortality. Among 13,028 included women, most had at least 1 prior screening (10 094 women [77.5%]) and were age... Read More

12 May, 2026

Global Stage Distribution of Breast Cancer at Diagnosis: A Systematic Review and Meta-Analysis

Javier David Benitez Fuentes, Eileen Morgan, Alicia de Luna Aguilar et al. JAMA Oncol. 2024 Jan 1;10(1):71-78

Objective: To assess the global distribution of breast cancer stage by country, age group, calendar period, and socioeconomic status using population-based data. Data were available for 2.4 million women with breast cancer from 81 countries. Globally, the proportion of cases with distant metastatic breast cancer at... Read More

12 May, 2026

Trends of Female Breast Cancer Burden in China over 25 Years: A Join Point Regression and Age-Period-Cohort Analysis Based on the GBD (1997-2021)

Yuanyan Tang, Jia Zhu and Zhengren Liu. Cancer Invest. 2025 Sep;43(8):610-622

This study analyzed the trends of BC among Chinese women from 1997 to 2021 to support evidence-based for the prevention, screening and treatment strategies of female BC in China. We extracted data on BC incidence, mortality, prevalence, disability-adjusted life years (DALYs), years lived with disability (YLDs) and... Read More

12 May, 2026

Breast Cancer Incidence Among US Women Aged 20 to 49 Years by Race, Stage, and Hormone Receptor Status

Shuai Xu, Sara Murtagh, Yunan Han,et al. JAMA Netw Open. 2024 Jan 2;7(1):e2353331

Breast cancer in young women has a less favorable prognosis compared with older women. This cross-sectional study used data from Surveillance, Epidemiology, and End Results 17 registries (2000-2019). Women aged 20 to 49 years with a primary invasive breast cancer were included. Out of 217 815 eligible women, the m... Read More

12 May, 2026

Global patterns and risk factors of breast cancer in women under 35: a population-based study

Dechuang Jiao, Jiujun Zhu, Dandan Wang, et al. Breast. 2026 Mar 23:87:104777

Accurate estimates of the global burden of young breast cancer (YBC) are lacking. In 2021, YBC accounted for substantial global disease burden, with 81,856 new cases, 687,819 prevalent cases, 18,597 deaths, and 1,178,721 DALYs. From 1990 to 2021, global ASIR (AAPC: 1.3%) and ASMR (AAPC: 0.3%) increased significant... Read More

12 May, 2026

The global burden of early-onset cancer in women, 1990-2021: findings from the GBD 2021 with focus on China

Yibei Li, Danqi Huang, Jingyi Liu, et al. J Natl Cancer Cent. 2026 Feb 11;6(2):149-158

Early-onset cancer is a significant public health threat in females, yet comprehensive data on its global burden and temporal trends remain limited. This study analyzed the incidence, mortality, and disability-adjusted life years (DALYs) of female early-onset cancers (ages 15-49 years) from 1990 to 2021, with proje... Read More

12 May, 2026

Cancer mortality projections through 2026 among young adults in 15 upper-middle and high-income countries with focus on colorectal cancer

Silvia Mignozzi, Claudia Santucci, Gianfranco Alicandro, et al. Cancer Causes Control. 2026 Apr 3;37(5):79

An increasing cancer incidence has been observed among recent generations over the last decade. However, apart from colorectal cancer, these increases were not associated with rises in mortality. We extracted death counts for individuals aged 25-49 from the WHO Mortality Database and population data from the UN Wo... Read More

12 May, 2026

Estimating global cancer survival and mortality from 1990 to 2050: a simulation-based analysis of 17 cancers

Zachary J Ward, Fabio Ynoe Moraes, Andrew M Scott, et al. Lancet Oncol. 2026 May;27(5):560-568

Cancer survival has improved in many countries in recent decades, but large disparities remain globally. Understanding the effects of workforce shortages, stage at diagnosis, and broader health system barriers on poor survival is important for the design and evaluation of policy interventions to improve cancer sur... Read More

12 May, 2026

Global, regional, and national burden of breast, cervical, uterine, and ovarian cancer and their risk factors among women from 1990 to 2021, and projections to 2050: findings from the global burden of disease study 2021

Yingying Li, Wenfu Song, Ping Gao, et al. BMC Cancer. 2025 Feb 24;25(1):330

Female breast cancer, cervical cancer, uterine cancer, and ovarian cancer (FBCUO) pose a significant threat to global public health. Incidence, age-standardized incidence rate (ASIR), deaths, age-standardized mortality rate (ASMR), disability-adjusted life years (DALYs), age-standardized rate of DALYs (ASDR), and ... Read More

12 May, 2026

Burden of female‐specific cancers in China from 1990 to 2021: A systematic analysis for the Global Burden of Disease Study 2021

Wenhui Ren, Xiangyu Guo, Zheng Liu, et al. Cancer. 2025;e35712. 1-11 wileyonlinelibrary.com/journal/cncr

Breast cancer and reproductive system cancers remain significant public health threats for Chinese women. The year‐ and age‐specific estimates of the incidence, mortality, and disability‐adjusted life‐years (DALYs) associated with breast, cervical, ovarian, and uterine cancers in China from 1990 to 2021 were gener... Read More

12 May, 2026