Cara Anthony, Blake Farmer. KFF Health News / Nashville Public Radio. 2026 Jun 16.
More than a dozen cancers are now rising among U.S. adults under 50, with colorectal and breast cancers increasing the most; colorectal cancer is now the deadliest cancer for Americans ages 18 to 49. No single cause has been ident...
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Colon cancer is highly treatable when caught early, with a five-year survival rate of roughly 90% for localized, early-stage disease, yet it is often difficult to diagnose because it can develop without symptoms or mimic benign co...
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On June 17, 2026, the leaders of the G7—joined by Brazil, Egypt, India, Kenya, and the Republic of Korea—issued a joint call to accelerate the global fight against cancer, a disease that kills nearly 10 million people a year and w...
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PATROL, a multicenter prospective study published in BJU International on June 9, screens men who carry an inherited pathogenic variant in a prostate cancer risk gene (BRCA2, BRCA1, ATM, CHEK2, HOXB13, and the Lynch syndrome genes...
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Ling Qi , Mengfei Sun, Weixin Liu, et al. Chin Med J (Engl). 2024 Dec 20;137(24):3108-3116
The aim of this study is to analyze the current burden of esophageal cancer in 185 countries in 2022 and to project the trends up to the year 2050. In 2022, an estimated 511,054 people were diagnosed with esophageal cancer globall...
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Hee Chul Yang, Austin Chang, Maxime Visa, et al. JAMA Netw Open. 2025 Nov 3;8(11):e2546222
Lung cancer is increasingly diagnosed in never-smokers, suggesting that the current US Preventive Services Task Force (USPSTF) screening criteria using low-dose computed tomography exclude many at-risk individuals, thus raising co...
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Doratha A Byrd, Victoria Damerell, Maria F Gomez Morales, et al. Int J Cancer. 2025 Jul 1;157(1):64-73
Colorectal cancer (CRC) is the second overall leading cause of cancer death in the United States, with recurrence being a frequent cause of mortality. The gut microbiome, reflected in fecal samples, is likely mechanistically linke...
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Evan Weber, Carlos A Carmona-Gonzalez, Melanie Boucher, et al. Curr Oncol. 2025 May 22;32(6):290
Pathogenic variants in breast cancer predisposition genes are associated with poor clinical outcomes but also offer an opportunity for more individualized therapeutic pathways. Given increasing knowledge, improvements in germline...
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Zoulikha Rezoug , Stephanie P Totten, David Szlachtycz, et al. JAMA Netw Open. 2024 Sep 3;7(9):e2431427
Between 5% and 10% of breast cancer cases are associated with an inherited germline pathogenic or likely pathogenic variant (GPV) in a breast cancer susceptibility gene (BCSG), which could alter local and systemic therapy recommen...
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Elham Kazemian , Qianxing Mo , Marco Matejcic, et al. J Natl Cancer Inst. 2025 Dec 1;117(12):2513-2525
Cancer-related fatigue (fatigue) is a common and persistent symptom after cancer treatment, yet the role of genetic susceptibility remains unclear. We used data from a prospective cohort study called the ColoCare Study, conducted...
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Kirkpatrick B Fergus, Katherine S Ross, Maren T Scheuner, et al. JAMA Intern Med. 2026 Mar 1;186(3):344-352
Among 23 098 women who completed germline genetic testing (mean age, 54.3 years), 714 (3.1%) carried a PV. Excluding 109 who were previously aware of their PV, the detection rate was 2.6%. PVs were most common in CHEK2 (337) and A...
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Karely M van Thiel Berghuijs, Heydon K Kaddas, et al. J Cancer Surviv. 2024 Jun;18(3):1075-1084
Employment and financial hardships are common issues for working-age colorectal cancer patients. We surveyed colorectal cancer survivors to investigate employment, insurance, and financial outcomes by age at diagnosis. There were...
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