Articles

Association between risk-reducing surgeries and survival in young BRCA carriers with breast cancer: an international cohort study

Eva Blondeaux1, Amir Sonnenblick, Elisa Agostinetto et al. Lancet Oncol. 2025 26(6):759-770

We investigated the association between risk-reducing mastectomy (RRM) or risk-reducing salpingo-oophorectomy (RRSO), or both procedures, with survival outcomes in a large global cohort of young BRCA carriers with previous breast cancer.  Between Jan 1, 2000, and Dec 31, 2020, 5290 patients were included, of whom ... Read More

24 Mar, 2026

Scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021

GBD 2021 Tobacco Forecasting Collaborators Lancet Public Health. 2024 Oct;9(10):e729-e744

Smoking is the leading behavioral risk factor for mortality globally, accounting for more than 175 million deaths and nearly 4·30 billion years of life lost (YLLs) from 1990 to 2021. The pace of decline in smoking prevalence has slowed in recent years for many countries, and although strategies have recently been p... Read More

24 Mar, 2026

The indirect costs of vaccine-preventable cancer mortality in the Middle East and North Africa (MENA)

Goran Bencinaa, Dzhumber Ugrekhelidzeb, Hayley Shoelc. Journal Of Medical Economics 2024, Vol. 27, NO. S2, 41–50

Infections are responsible for 13% of cancer cases worldwide, with human papillomavirus (HPV) and hepatitis B (HBV) among the infections associated with cancer for which vaccines are available. The aim of this study was to estimate the indirect cost of premature mortality related to cancers caused by HPV and HBV in... Read More

24 Mar, 2026

Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States

Farhad Islami MD, Emily C. Marlow, Blake Thomson, et al. CA Cancer J Clin. 2024;74:405–432

The authors estimated the proportion and number of invasive cancer cases (excluding nonmelanoma skin cancers) and deaths, overall and for 30 cancer types among adults who were aged 30 years and older in 2019 in the United States, that were attributable to potentially modifiable risk factors. These included cigarett... Read More

24 Mar, 2026

Global and regional cancer burden attributable to modifiable risk factors to inform prevention

Hanna Fink, Oliver Langselius, Jérôme Vignat, Harriet Rumgay, et al. Nature Medicine. Published online: 03 February 2026

We estimated the 2022 global and national cancer burden attributable to 30 such factors, including tobacco smoking, alcohol consumption, high body mass index, insufficient physical activity, smokeless tobacco and areca nut, suboptimal breastfeeding, air pollution, ultraviolet radiation, 9 infectious agents and 13 o... Read More

24 Mar, 2026

Estimation of Cancer Deaths Averted from Prevention, Screening, and Treatment Efforts, 1975-2020

Katrina A. B. Goddard; Eric J. Feuer; Jeanne S. Mandelblatt; et al. JAMA Oncol. 2025;11(2):162-167.

The contributions of different interventions across the cancer control continuum was evaluated with primary prevention via smoking reduction (lung), screening for interception (cervix and colorectal) or early detection (breast, cervix, colorectal, and prostate), and therapy (breast, colorectal, lung, and prostate).... Read More

24 Mar, 2026

Cancer mortality predictions for 2025 in Latin America with focus on prostate cancer

Silvia Mignozzi, Claudia Santucci, Fabio Levi, et al. Eur J Cancer Prev. 2026 Mar 1;35(2):97-107.

We provided cancer mortality rate estimates for the year 2025 in six Latin American countries (Argentina, Brazil, Chile, Colombia, Cuba, and Mexico), focusing on prostate cancer. We extracted mortality data for all cancers combined and the most common sites from the WHO and population data since 1970 from the Unite... Read More

24 Mar, 2026

Variability and social patterning of cancer mortality in 343 Latin American cities: an ecological study

Tania Alfaro, Kevin Martinez-Folgar, Dalia Stern, et al. Lancet Glob Health. 2025 Feb;13(2):e268-e276.

Understanding between-city variations in cancer mortality is crucial to inform national and subnational cancer prevention strategies. As part of the Salud Urbana en América Latina (SALURBAL) project, we aimed to describe the variability in cancer mortality rates across 343 cities in nine Latin American countries an... Read More

24 Mar, 2026

Cervical cancer in sub-Saharan Africa: an urgent call for improving accessibility and use of preventive services

Tafadzwa Dzinamarira 1 2, Enos Moyo 3, Mathias Dzobo 4, Elliot Mbunge 5, Grant Murewanhema 6 Int J Gynecol Cancer. 2023 Apr 3;33(4):592-597

Sub-Saharan Africa has the highest rates of cervical cancer in the world, largely attributed to low cervical cancer screening coverage. Cervical cancer is the most common cause of death among women in 21 of the 48 countries in sub-Saharan Africa. Close to 100% of all cases of cervical cancer are attributable to Hum... Read More

24 Mar, 2026

Comparative examination of breast cancer burden in sub-Saharan Africa, 1990-2019: estimates from Global Burden of Disease 2019 study

Kenechukwu Kizito Igbokwe BMJ Open. 2024 Mar 29;14(3):e082492

This study aimed to evaluate the most up-to-date burden of female breast cancer and analyze the leading risk factors in countries and regions in sub-Saharan Africa. In sub-Saharan Africa, the incidences of breast cancer increased by 247% in 2019 from 1990, with the highest incidence recorded in Nigeria. The deaths ... Read More

23 Mar, 2026